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Multiple Choice

Which Westguard rule among the following is used to indicate systemic error?

A pattern where many control measurements drift in the same direction within a single run signals a bias or systemic error in the process. The rule that best captures this is the one requiring four consecutive control results to exceed the mean by more than 1 standard deviation on the same side. When you see four in a row all high or all low by at least 1 SD, it shows a persistent shift rather than random scatter, indicating systematic error in the method, instrument, or reagents. Two consecutive results beyond 2 SD on the same side points to unusual variation but isn’t as directly tied to a consistent bias across the run. The rule that looks at the range between two adjacent results exceeding 4 SD flags instability within the run (imprecision or outliers) rather than a steady bias. The mixed pattern where one value goes beyond 1 SD and the next beyond 3 SD is a warning signal and not as definitive for a sustained bias as the four-in-a-row 1 SD pattern. So, the rule that indicates systemic error is the one describing four consecutive results beyond 1 SD on the same side.

A pattern where many control measurements drift in the same direction within a single run signals a bias or systemic error in the process. The rule that best captures this is the one requiring four consecutive control results to exceed the mean by more than 1 standard deviation on the same side. When you see four in a row all high or all low by at least 1 SD, it shows a persistent shift rather than random scatter, indicating systematic error in the method, instrument, or reagents.

Two consecutive results beyond 2 SD on the same side points to unusual variation but isn’t as directly tied to a consistent bias across the run. The rule that looks at the range between two adjacent results exceeding 4 SD flags instability within the run (imprecision or outliers) rather than a steady bias. The mixed pattern where one value goes beyond 1 SD and the next beyond 3 SD is a warning signal and not as definitive for a sustained bias as the four-in-a-row 1 SD pattern.

So, the rule that indicates systemic error is the one describing four consecutive results beyond 1 SD on the same side.