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Multiple Choice

Which urine finding is most consistent with nephrotic syndrome?

In nephrotic syndrome, the kidneys leak large amounts of protein and lipids into the urine, so you see lipiduria alongside heavy proteinuria. Oval fat bodies are lipid-laden tubular cells that appear in the urine and, under microscopy, reflect this lipiduria. The combination of protein detected in urine and oval fat bodies is the classic pattern for nephrotic syndrome. The other options point to different conditions: bacteria with nitrite and WBCs suggests a urinary tract infection, Trichomonas vaginitis is a vaginal/urinary tract parasite, and amorphous urates are common, non-specific crystals not uniquely linked to nephrotic syndrome.

In nephrotic syndrome, the kidneys leak large amounts of protein and lipids into the urine, so you see lipiduria alongside heavy proteinuria. Oval fat bodies are lipid-laden tubular cells that appear in the urine and, under microscopy, reflect this lipiduria. The combination of protein detected in urine and oval fat bodies is the classic pattern for nephrotic syndrome.

The other options point to different conditions: bacteria with nitrite and WBCs suggests a urinary tract infection, Trichomonas vaginitis is a vaginal/urinary tract parasite, and amorphous urates are common, non-specific crystals not uniquely linked to nephrotic syndrome.