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Multiple Choice

Which urinary sediment element is a waxy cast typically associated with protein positivity?

Waxy casts are broad, dull, waxy-looking urinary casts that form in long-standing, low-flow tubular conditions. They arise when casts age and degrade as they travel through dilated tubules, giving them a broad, refractile, waxy appearance. This aging process often occurs in the setting of significant protein leakage into the urine, so they’re typically seen with protein positivity on urinalysis. In contrast, hyaline casts are colorless and non-waxy, granular casts come from degenerated cellular material, and RBC casts reflect bleeding into the tubules. Therefore, the waxy cast paired with positive protein is the best fit.

Waxy casts are broad, dull, waxy-looking urinary casts that form in long-standing, low-flow tubular conditions. They arise when casts age and degrade as they travel through dilated tubules, giving them a broad, refractile, waxy appearance. This aging process often occurs in the setting of significant protein leakage into the urine, so they’re typically seen with protein positivity on urinalysis. In contrast, hyaline casts are colorless and non-waxy, granular casts come from degenerated cellular material, and RBC casts reflect bleeding into the tubules. Therefore, the waxy cast paired with positive protein is the best fit.