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Multiple Choice

Which urinary sediment element is a red blood cell cast?

A red blood cell cast appears when red blood cells get trapped in a protein matrix within the tubules. This happens when there’s damage to the glomerular capillaries, allowing RBCs to leak into the filtrate, and they become incorporated into a cast formed from Tamm-Horsfall protein. Seeing an RBC cast is a strong sign of glomerular or nephritic-type pathology, which is why this option is the best description for a red blood cell cast. In contrast, hyaline casts are acellular protein casts that can form with dehydration or mild kidney stress and don’t contain cells. Ova are parasite eggs and not a cast at all, and mucous refers to mucous strands rather than a cellular cast.

A red blood cell cast appears when red blood cells get trapped in a protein matrix within the tubules. This happens when there’s damage to the glomerular capillaries, allowing RBCs to leak into the filtrate, and they become incorporated into a cast formed from Tamm-Horsfall protein. Seeing an RBC cast is a strong sign of glomerular or nephritic-type pathology, which is why this option is the best description for a red blood cell cast.

In contrast, hyaline casts are acellular protein casts that can form with dehydration or mild kidney stress and don’t contain cells. Ova are parasite eggs and not a cast at all, and mucous refers to mucous strands rather than a cellular cast.