Which substances can cause a false decrease in Trinder's glucose oxidase readings?

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Multiple Choice

Which substances can cause a false decrease in Trinder's glucose oxidase readings?

In Trinder's glucose oxidase readings, the color you measure comes from a reaction that uses hydrogen peroxide produced when glucose is oxidized. Substances that interfere can either consume hydrogen peroxide or alter the color signal, leading to a reading that’s falsely low. Uric acid and Vitamin C are reducing agents; they can scavenge hydrogen peroxide or reduce the oxidized color, so less color develops than actually should. Bilirubin and hemoglobin are colored compounds that absorb light at the assay’s measurement wavelength, which can distort the color readout and make the result appear lower. Bleach and icodextrin aren’t typical agents that cause this specific false decrease in routine Trinder readings, so they don’t fit as well as the others.

In Trinder's glucose oxidase readings, the color you measure comes from a reaction that uses hydrogen peroxide produced when glucose is oxidized. Substances that interfere can either consume hydrogen peroxide or alter the color signal, leading to a reading that’s falsely low.

Uric acid and Vitamin C are reducing agents; they can scavenge hydrogen peroxide or reduce the oxidized color, so less color develops than actually should. Bilirubin and hemoglobin are colored compounds that absorb light at the assay’s measurement wavelength, which can distort the color readout and make the result appear lower.

Bleach and icodextrin aren’t typical agents that cause this specific false decrease in routine Trinder readings, so they don’t fit as well as the others.

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