Which substance is found in urine under acidic conditions?

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Acidic urine can cause certain substances to crystallize because their solubility changes with pH. Tyrosine is one of those amino acids whose solubility decreases in acidic conditions, so it tends to precipitate and be found in urine when the urine is acidic. This happens because the amino acid becomes less ionized in acidic environments, reducing its interaction with water and promoting crystal formation. In clinical urine analysis, tyrosine crystals are a recognized finding, often associated with liver disease or metabolic disorders that raise tyrosine levels. The other options are not as directly tied to urine acidity: cholesterol crystals relate more to nephrotic syndrome, leucine crystals are also linked to liver disease but are less specifically tied to acidic urine, and sulfonamide crystals depend on drug presence rather than a general pH effect.