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Multiple Choice

Which statement about glomerulonephritis is accurate regarding blood analytes?

Loss of proteins into the urine from glomerular inflammation lowers the amount of protein circulating in the blood. This urinary protein loss, especially of albumin, reduces the total protein level in plasma (hypoproteinemia), which is a direct blood analyte change you’d expect in glomerular disease. While blood urea can rise with impaired kidney function and urine or CSF protein levels reflect different compartments, the most characteristic blood finding here is decreased total blood protein due to proteinuria.

Loss of proteins into the urine from glomerular inflammation lowers the amount of protein circulating in the blood. This urinary protein loss, especially of albumin, reduces the total protein level in plasma (hypoproteinemia), which is a direct blood analyte change you’d expect in glomerular disease. While blood urea can rise with impaired kidney function and urine or CSF protein levels reflect different compartments, the most characteristic blood finding here is decreased total blood protein due to proteinuria.