Which statement about albumin measurement bias using bromcresol Green is true?

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Bromcresol green dye-binding assays measure albumin by binding dye to the protein, but the dye can also interact with other serum proteins. When albumin is present at low levels, the contribution from non‑albumin interactions to the dye signal becomes relatively larger, causing the readout to appear higher than the true albumin concentration. That makes this method biased toward overestimation at low albumin levels. It’s a distinct issue from using bromcresol purple, which has a different interference profile, and it’s certainly not unbiased. So the statement that it overestimates albumin concentration when low best describes the bias.