Which specimen collection tube is associated with the potential for erroneous uric acid results due to additives?

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Multiple Choice

Which specimen collection tube is associated with the potential for erroneous uric acid results due to additives?

Additives in the specimen collection tube can change how a chemical test works. Uric acid is often measured with an enzymatic reaction, and the reagents involved can be affected by substances present in the tube. Sodium fluoride, found in gray-top tubes, can interfere with some uric acid assays by inhibiting the enzymes or altering the reaction conditions, which can lead to inaccurate results. Because of this potential interference, specimens collected in fluoride-containing tubes may yield erroneous uric acid measurements depending on the method used. Tubes without this additive or with different anticoagulants generally don’t raise the same interference risk for this assay.

Additives in the specimen collection tube can change how a chemical test works. Uric acid is often measured with an enzymatic reaction, and the reagents involved can be affected by substances present in the tube. Sodium fluoride, found in gray-top tubes, can interfere with some uric acid assays by inhibiting the enzymes or altering the reaction conditions, which can lead to inaccurate results. Because of this potential interference, specimens collected in fluoride-containing tubes may yield erroneous uric acid measurements depending on the method used. Tubes without this additive or with different anticoagulants generally don’t raise the same interference risk for this assay.

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