Which pattern best fits hyperaldosteronism (Conn's disease)?

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Multiple Choice

Which pattern best fits hyperaldosteronism (Conn's disease)?

Excess aldosterone in Conn's disease pushes the kidneys to reabsorb more sodium in the distal nephron while increasing potassium (and hydrogen) secretion. That sodium retention raises serum sodium and expands extracellular fluid, often with hypertension, while the increased potassium loss drives hypokalemia. The kidneys also excrete more potassium, so urinary potassium excretion is high. This combination—higher sodium, lower potassium, and high urinary potassium—fits hyperaldosteronism best. Patterns with low sodium and high potassium, normal electrolytes, or abnormalities not driven by aldosterone (like elevated magnesium) don’t match the hormonal effect seen in Conn's disease.

Excess aldosterone in Conn's disease pushes the kidneys to reabsorb more sodium in the distal nephron while increasing potassium (and hydrogen) secretion. That sodium retention raises serum sodium and expands extracellular fluid, often with hypertension, while the increased potassium loss drives hypokalemia. The kidneys also excrete more potassium, so urinary potassium excretion is high. This combination—higher sodium, lower potassium, and high urinary potassium—fits hyperaldosteronism best. Patterns with low sodium and high potassium, normal electrolytes, or abnormalities not driven by aldosterone (like elevated magnesium) don’t match the hormonal effect seen in Conn's disease.

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