Which pair correctly matches a cancer marker with its tissue?

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Multiple Choice

Which pair correctly matches a cancer marker with its tissue?

Tumor markers often reflect the tissue they come from. CA-125 is a glycoprotein produced by cells derived from the coelomic epithelium, including the ovarian surface epithelium, so its levels rise most noticeably in ovarian epithelial cancers. It’s commonly used to monitor disease course and response to treatment in ovarian cancer, though it’s not perfect for screening and can be elevated in other conditions. CA-19-9 is linked mainly to pancreatic and biliary tract cancers, not ovarian. CA-15-3 is linked to breast cancer, used to monitor advanced disease. Therefore, the correct match is CA-125 with ovarian tissue.

Tumor markers often reflect the tissue they come from. CA-125 is a glycoprotein produced by cells derived from the coelomic epithelium, including the ovarian surface epithelium, so its levels rise most noticeably in ovarian epithelial cancers. It’s commonly used to monitor disease course and response to treatment in ovarian cancer, though it’s not perfect for screening and can be elevated in other conditions. CA-19-9 is linked mainly to pancreatic and biliary tract cancers, not ovarian. CA-15-3 is linked to breast cancer, used to monitor advanced disease. Therefore, the correct match is CA-125 with ovarian tissue.

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