Which marker would be used to screen for prostate cancer?

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Multiple Choice

Which marker would be used to screen for prostate cancer?

Screening for prostate cancer commonly uses a blood marker that measures total PSA. Prostate-specific antigen is produced by the prostate, and higher levels in the blood can indicate prostate pathology, including cancer. It’s chosen for screening because it’s relatively specific to the prostate, helping identify men who need further evaluation. The other markers link to cancers in different organs: CEA with colorectal cancer, CA 125 with ovarian cancer, and AFP with liver cancer and some germ cell tumors. Remember, PSA testing isn’t perfect—elevations can occur with benign conditions too—so abnormal results lead to additional tests like imaging or biopsy to confirm.

Screening for prostate cancer commonly uses a blood marker that measures total PSA. Prostate-specific antigen is produced by the prostate, and higher levels in the blood can indicate prostate pathology, including cancer. It’s chosen for screening because it’s relatively specific to the prostate, helping identify men who need further evaluation. The other markers link to cancers in different organs: CEA with colorectal cancer, CA 125 with ovarian cancer, and AFP with liver cancer and some germ cell tumors. Remember, PSA testing isn’t perfect—elevations can occur with benign conditions too—so abnormal results lead to additional tests like imaging or biopsy to confirm.

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