Which diagnostic test result most strongly supports cystic fibrosis in this context?

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Multiple Choice

Which diagnostic test result most strongly supports cystic fibrosis in this context?

When cystic fibrosis is suspected, the most informative finding is a sweat test showing unusually high salt content. The CFTR defect in sweat glands causes defective reabsorption of chloride and sodium, so sweat becomes very salty. A sweat osmolality of 70 mmol/L indicates a high level of salts in sweat and strongly supports CF in the appropriate clinical setting. Amylase elevation can reflect pancreatitis or gland issues, not CF diagnosis. LDL levels aren’t indicative of CF. Elevated blood glucose can occur in CF patients but does not by itself confirm the disease.

When cystic fibrosis is suspected, the most informative finding is a sweat test showing unusually high salt content. The CFTR defect in sweat glands causes defective reabsorption of chloride and sodium, so sweat becomes very salty. A sweat osmolality of 70 mmol/L indicates a high level of salts in sweat and strongly supports CF in the appropriate clinical setting.

Amylase elevation can reflect pancreatitis or gland issues, not CF diagnosis. LDL levels aren’t indicative of CF. Elevated blood glucose can occur in CF patients but does not by itself confirm the disease.

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