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Multiple Choice

Which diagnosis is most likely given WBC casts in urine and moderate bacteria?

WBC casts in urine signal infection or inflammation that involves the kidney’s tubules. When bacteria are present in the urine along with these casts, it points to an ascending infection that has reached the kidneys—pyelonephritis. Acute cystitis is a bladder infection and can show bacteria and white cells in urine, but it typically doesn’t produce WBC casts, which reflect renal tubular involvement. Glomerulonephritis involves the glomeruli and usually shows red blood cell casts and proteinuria rather than WBC casts alone. Urolithiasis (stones) can cause pain and hematuria but not the kind of WBC casts seen with kidney involvement. So, the combination of WBC casts with bacteria most strongly points to pyelonephritis.

WBC casts in urine signal infection or inflammation that involves the kidney’s tubules. When bacteria are present in the urine along with these casts, it points to an ascending infection that has reached the kidneys—pyelonephritis.

Acute cystitis is a bladder infection and can show bacteria and white cells in urine, but it typically doesn’t produce WBC casts, which reflect renal tubular involvement. Glomerulonephritis involves the glomeruli and usually shows red blood cell casts and proteinuria rather than WBC casts alone. Urolithiasis (stones) can cause pain and hematuria but not the kind of WBC casts seen with kidney involvement.

So, the combination of WBC casts with bacteria most strongly points to pyelonephritis.