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Multiple Choice

Which condition is associated with elevated CORT levels?

Elevated cortisol happens when the pituitary-adrenal system is pushed to produce more hormone than normal. In Cushing's disease, a pituitary tumor makes excess ACTH, which tells the adrenal cortex to release too much cortisol. That overproduction of cortisol is exactly what raises CORT levels. Addison's disease, by contrast, is adrenal failure and results in low cortisol. Hypothyroidism involves thyroid hormone and doesn’t inherently raise cortisol, and nephrotic syndrome is a kidney condition with no direct effect on cortisol production.

Elevated cortisol happens when the pituitary-adrenal system is pushed to produce more hormone than normal. In Cushing's disease, a pituitary tumor makes excess ACTH, which tells the adrenal cortex to release too much cortisol. That overproduction of cortisol is exactly what raises CORT levels. Addison's disease, by contrast, is adrenal failure and results in low cortisol. Hypothyroidism involves thyroid hormone and doesn’t inherently raise cortisol, and nephrotic syndrome is a kidney condition with no direct effect on cortisol production.