Which analyte shows binaural variation with AM levels higher than PM levels?

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Multiple Choice

Which analyte shows binaural variation with AM levels higher than PM levels?

Cortisol shows a clear diurnal rhythm: levels rise after waking (the cortisol awakening response) and then gradually fall throughout the day, so morning values are higher than evening values. This makes cortisol the analyte that tends to have higher AM than PM levels. The other analytes don’t have a consistent, robust morning-peak pattern—creatine kinase mainly tracks muscle activity or injury, lactate varies with exercise and metabolic demand, and CSF porphyrins don’t exhibit a reliable diurnal rise. So, cortisol is the best match for showing higher morning levels compared with the evening.

Cortisol shows a clear diurnal rhythm: levels rise after waking (the cortisol awakening response) and then gradually fall throughout the day, so morning values are higher than evening values. This makes cortisol the analyte that tends to have higher AM than PM levels. The other analytes don’t have a consistent, robust morning-peak pattern—creatine kinase mainly tracks muscle activity or injury, lactate varies with exercise and metabolic demand, and CSF porphyrins don’t exhibit a reliable diurnal rise. So, cortisol is the best match for showing higher morning levels compared with the evening.

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