Which analyte is tested on EDTA tubes such as HgA1C in non-serum samples?

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Multiple Choice

Which analyte is tested on EDTA tubes such as HgA1C in non-serum samples?

HbA1c is determined from red blood cells, so it requires a whole-blood sample collected in an anticoagulant like EDTA to keep the cells intact and prevent clotting. This preserves the hemoglobin and its glycated form so the test can accurately reflect long-term glucose exposure. Serum lacks red blood cells, so HbA1c measurements need non-serum (EDTA) samples. The other options are typically measured in serum (or plasma) rather than whole blood, so they don’t rely on the cellular component that HbA1c requires.

HbA1c is determined from red blood cells, so it requires a whole-blood sample collected in an anticoagulant like EDTA to keep the cells intact and prevent clotting. This preserves the hemoglobin and its glycated form so the test can accurately reflect long-term glucose exposure. Serum lacks red blood cells, so HbA1c measurements need non-serum (EDTA) samples.

The other options are typically measured in serum (or plasma) rather than whole blood, so they don’t rely on the cellular component that HbA1c requires.

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