Which analyte is affected by hemolysis and is a common marker of energy metabolism?

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Multiple Choice

Which analyte is affected by hemolysis and is a common marker of energy metabolism?

Creatine kinase is a key player in cellular energy management because it catalyzes the transfer of a phosphate from phosphocreatine to ADP to rapidly regenerate ATP in muscle and brain during bursts of activity. That makes CK a common marker of energy metabolism and muscle demand. When a blood sample is hemolyzed, rupture of red blood cells releases contents that can interfere with enzyme assays and often raise measured CK levels, leading to misleading results. The other options don’t serve as a primary energy-metabolism marker: magnesium is a mineral essential for many reactions, sodium is a major electrolyte, and ammonia is tied more to nitrogen metabolism and liver function.

Creatine kinase is a key player in cellular energy management because it catalyzes the transfer of a phosphate from phosphocreatine to ADP to rapidly regenerate ATP in muscle and brain during bursts of activity. That makes CK a common marker of energy metabolism and muscle demand. When a blood sample is hemolyzed, rupture of red blood cells releases contents that can interfere with enzyme assays and often raise measured CK levels, leading to misleading results. The other options don’t serve as a primary energy-metabolism marker: magnesium is a mineral essential for many reactions, sodium is a major electrolyte, and ammonia is tied more to nitrogen metabolism and liver function.

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