Which analyte is affected by icterus and is a gonadal hormone?

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Multiple Choice

Which analyte is affected by icterus and is a gonadal hormone?

Icterus (high bilirubin) can interfere with laboratory assays that rely on optical detection, since bilirubin absorbs light and can bias colorimetric readings. Among the hormones listed, testosterone is a gonadal hormone produced by the testes. In many common assay formats for testosterone, bilirubin interference is a known issue, making its measurement more susceptible to distortion in icteric samples. Estradiol is also a gonadal hormone, but in typical clinical screening, testosterone measurements are more commonly affected by bilirubin in the assays used, which is why testosterone is the best match here. PTH and LH are not gonadal hormones, so they don’t fit the criteria.

Icterus (high bilirubin) can interfere with laboratory assays that rely on optical detection, since bilirubin absorbs light and can bias colorimetric readings. Among the hormones listed, testosterone is a gonadal hormone produced by the testes. In many common assay formats for testosterone, bilirubin interference is a known issue, making its measurement more susceptible to distortion in icteric samples. Estradiol is also a gonadal hormone, but in typical clinical screening, testosterone measurements are more commonly affected by bilirubin in the assays used, which is why testosterone is the best match here. PTH and LH are not gonadal hormones, so they don’t fit the criteria.

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