What is the role of the Parathyroid Hormone?

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Multiple Choice

What is the role of the Parathyroid Hormone?

Parathyroid hormone raises blood calcium through coordinated actions on bone, kidney, and gut. It stimulates osteoblasts to express RANKL, which activates osteoclasts and drives bone resorption, releasing calcium into the bloodstream. In the kidney, it increases calcium reabsorption in the distal tubule and promotes phosphate excretion, lowering serum phosphate. It also upregulates 1-alpha-hydroxylase, activating vitamin D (calcitriol), which boosts intestinal absorption of calcium (and phosphate). In total, PTH raises calcium, lowers phosphate, and activates vitamin D, which is why this option best captures its role.

Parathyroid hormone raises blood calcium through coordinated actions on bone, kidney, and gut. It stimulates osteoblasts to express RANKL, which activates osteoclasts and drives bone resorption, releasing calcium into the bloodstream. In the kidney, it increases calcium reabsorption in the distal tubule and promotes phosphate excretion, lowering serum phosphate. It also upregulates 1-alpha-hydroxylase, activating vitamin D (calcitriol), which boosts intestinal absorption of calcium (and phosphate). In total, PTH raises calcium, lowers phosphate, and activates vitamin D, which is why this option best captures its role.

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