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Multiple Choice

What is a stimulation test?

A stimulation test involves giving a stimulating hormone or agent to prompt the target gland to release its hormone, and then checking whether that hormone (or a downstream product) rises. This dynamic approach shows how well the gland can respond to stimulation, not just what its resting level is. For example, an ACTH stimulation test uses synthetic ACTH to see if cortisol increases, revealing adrenal reserve. Basal measurement without any stimulus only shows the current level, not responsiveness; imaging after stimulation isn’t the defining feature of a stimulation test; and a suppression test looks at what happens when the axis is dampened, not stimulated.

A stimulation test involves giving a stimulating hormone or agent to prompt the target gland to release its hormone, and then checking whether that hormone (or a downstream product) rises. This dynamic approach shows how well the gland can respond to stimulation, not just what its resting level is. For example, an ACTH stimulation test uses synthetic ACTH to see if cortisol increases, revealing adrenal reserve. Basal measurement without any stimulus only shows the current level, not responsiveness; imaging after stimulation isn’t the defining feature of a stimulation test; and a suppression test looks at what happens when the axis is dampened, not stimulated.