In suspected pyelonephritis, which analyte would be affected and how?

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Multiple Choice

In suspected pyelonephritis, which analyte would be affected and how?

When the kidneys are inflamed in pyelonephritis, their filtering ability can drop, so waste products that the kidneys normally remove accumulate in the blood. Urea, produced from protein breakdown in the liver, is cleared by the kidneys; if filtration falls, urea levels in the blood rise. So, the expected change is an increase in urea. Protein in the urine or increases in total protein can occur in various conditions, but they are not as directly tied to the impaired clearance seen in kidney infection as the rise in urea is.

When the kidneys are inflamed in pyelonephritis, their filtering ability can drop, so waste products that the kidneys normally remove accumulate in the blood. Urea, produced from protein breakdown in the liver, is cleared by the kidneys; if filtration falls, urea levels in the blood rise. So, the expected change is an increase in urea. Protein in the urine or increases in total protein can occur in various conditions, but they are not as directly tied to the impaired clearance seen in kidney infection as the rise in urea is.

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