In nephrotic syndrome, which analyte is not increased?

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Multiple Choice

In nephrotic syndrome, which analyte is not increased?

In nephrotic syndrome, heavy protein loss in the urine causes a drop in circulating proteins, especially albumin, so total protein in the blood decreases rather than increases. At the same time, the liver ramps up lipoprotein production to compensate for hypoalbuminemia, leading to high lipid levels in the blood. That’s why cholesterol and triglycerides rise (increased CHOL and TRIG, and often TCHOL as a measure of cholesterol), while total protein falls. So the analyte that is not increased is the total protein, which is decreased.

In nephrotic syndrome, heavy protein loss in the urine causes a drop in circulating proteins, especially albumin, so total protein in the blood decreases rather than increases. At the same time, the liver ramps up lipoprotein production to compensate for hypoalbuminemia, leading to high lipid levels in the blood. That’s why cholesterol and triglycerides rise (increased CHOL and TRIG, and often TCHOL as a measure of cholesterol), while total protein falls. So the analyte that is not increased is the total protein, which is decreased.

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