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Multiple Choice

In a hyperthyroid patient, which lipid parameter is decreased?

Hyperthyroidism speeds up lipid metabolism and clearance. Thyroid hormones increase the liver’s LDL receptors, so more LDL particles are removed from the blood, and they also boost the conversion of cholesterol into bile acids, reducing the overall circulating cholesterol pool. Because total cholesterol reflects the overall amount of cholesterol present in the bloodstream, it tends to decrease reliably in this state. Triglycerides and individual lipoprotein fractions can vary and are less consistently reduced, so the clearest, most consistent decrease seen in hyperthyroidism is in cholesterol.

Hyperthyroidism speeds up lipid metabolism and clearance. Thyroid hormones increase the liver’s LDL receptors, so more LDL particles are removed from the blood, and they also boost the conversion of cholesterol into bile acids, reducing the overall circulating cholesterol pool. Because total cholesterol reflects the overall amount of cholesterol present in the bloodstream, it tends to decrease reliably in this state. Triglycerides and individual lipoprotein fractions can vary and are less consistently reduced, so the clearest, most consistent decrease seen in hyperthyroidism is in cholesterol.