If glomerulonephritis is suspected, which analytes would be affected and how would they appear?

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Multiple Choice

If glomerulonephritis is suspected, which analytes would be affected and how would they appear?

Glomerulonephritis damages the glomerular filtration barrier, so proteins leak into the urine (proteinuria) and waste products build up in the blood due to reduced filtration (azotemia). This combination lowers serum total protein because proteins are lost in urine, raises blood urea (urea) from impaired clearance, and increases protein in urine. So the best pattern is decreased serum total protein, increased blood urea, and increased urinary protein.

Glomerulonephritis damages the glomerular filtration barrier, so proteins leak into the urine (proteinuria) and waste products build up in the blood due to reduced filtration (azotemia). This combination lowers serum total protein because proteins are lost in urine, raises blood urea (urea) from impaired clearance, and increases protein in urine.

So the best pattern is decreased serum total protein, increased blood urea, and increased urinary protein.

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