If an add-on LDH test is requested on a cold-stored sample, what should you do?

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Multiple Choice

If an add-on LDH test is requested on a cold-stored sample, what should you do?

LDH testing is sensitive to how a specimen is handled after collection. If a sample has been stored cold, enzyme activity can shift and the result may not reflect the patient’s true LDH level. For an add-on test, you want a specimen that has not been compromised by storage conditions, so the most reliable approach is to reject the current cold-stored sample and obtain a fresh one. Warming the sample can introduce artifacts or further alter LDH, and proceeding with the existing specimen risks an inaccurate result. Recollecting a new specimen ensures the test reflects the patient’s actual LDH level under proper handling.

LDH testing is sensitive to how a specimen is handled after collection. If a sample has been stored cold, enzyme activity can shift and the result may not reflect the patient’s true LDH level. For an add-on test, you want a specimen that has not been compromised by storage conditions, so the most reliable approach is to reject the current cold-stored sample and obtain a fresh one. Warming the sample can introduce artifacts or further alter LDH, and proceeding with the existing specimen risks an inaccurate result. Recollecting a new specimen ensures the test reflects the patient’s actual LDH level under proper handling.

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