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Multiple Choice

GGT ordered for a specimen. Which factor can cause incorrect results?

GGT measurements are affected by preanalytical conditions, especially time and temperature before analysis. The biggest risk for erroneous results is delaying processing beyond 24 hours, because enzyme activity and the sample’s composition can change during storage, leading to falsely high or low results. Keeping a specimen for reanalysis at 2-8°C helps preserve the enzyme and reduce such changes, so this cold storage is protective rather than a source of error. Exposure to light isn’t typically a major factor for GGT assays, and room temperature storage for reanalysis can introduce some instability, but the critical risk is the prolonged delay before analysis.

GGT measurements are affected by preanalytical conditions, especially time and temperature before analysis. The biggest risk for erroneous results is delaying processing beyond 24 hours, because enzyme activity and the sample’s composition can change during storage, leading to falsely high or low results. Keeping a specimen for reanalysis at 2-8°C helps preserve the enzyme and reduce such changes, so this cold storage is protective rather than a source of error. Exposure to light isn’t typically a major factor for GGT assays, and room temperature storage for reanalysis can introduce some instability, but the critical risk is the prolonged delay before analysis.