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Multiple Choice

For Conn's disease suspicion, which specimen shows a potassium change and in what direction?

Excess aldosterone in Conn’s disease drives more potassium to be secreted into the distal nephron, so the kidneys waste potassium. That means urine potassium rises compared with normal. While serum potassium often falls because of this renal loss, the specific specimen showing the change in direction asked here is urine potassium, which increases.

Excess aldosterone in Conn’s disease drives more potassium to be secreted into the distal nephron, so the kidneys waste potassium. That means urine potassium rises compared with normal. While serum potassium often falls because of this renal loss, the specific specimen showing the change in direction asked here is urine potassium, which increases.