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Multiple Choice

CA-125 is most commonly linked to which cancer?

CA-125 is a tumor marker most closely associated with ovarian cancer. It’s produced by cells lining the peritoneum and by ovarian epithelial tumors, so its levels in the blood often rise as ovarian cancer progresses. Clinically, CA-125 is used to monitor treatment response and detect recurrence in patients known to have ovarian cancer, rather than for broad screening. It can be elevated in a variety of benign conditions (like endometriosis or menstruation) and in other diseases, which is why it’s not specific enough to diagnose ovarian cancer on its own. Other cancers have their own more characteristic markers, such as CA19-9 for pancreatic cancer, CA15-3 for breast cancer, and various markers for lung cancer, but CA-125 is most commonly linked to ovarian cancer.

CA-125 is a tumor marker most closely associated with ovarian cancer. It’s produced by cells lining the peritoneum and by ovarian epithelial tumors, so its levels in the blood often rise as ovarian cancer progresses. Clinically, CA-125 is used to monitor treatment response and detect recurrence in patients known to have ovarian cancer, rather than for broad screening. It can be elevated in a variety of benign conditions (like endometriosis or menstruation) and in other diseases, which is why it’s not specific enough to diagnose ovarian cancer on its own. Other cancers have their own more characteristic markers, such as CA19-9 for pancreatic cancer, CA15-3 for breast cancer, and various markers for lung cancer, but CA-125 is most commonly linked to ovarian cancer.