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Multiple Choice

A sweat osmolality of 70 mmol/L supports which diagnosis?

A sweat osmolality of 70 mmol/L indicates salty sweat, which is characteristic of cystic fibrosis. In CF, the CFTR chloride channel in the sweat ducts is defective, so sodium and chloride reabsorption is impaired and sweat remains unusually salty. This elevated salt content shows up as higher osmolality. The other conditions listed don’t cause this salty-sweat pattern, so they don’t fit this clue.

A sweat osmolality of 70 mmol/L indicates salty sweat, which is characteristic of cystic fibrosis. In CF, the CFTR chloride channel in the sweat ducts is defective, so sodium and chloride reabsorption is impaired and sweat remains unusually salty. This elevated salt content shows up as higher osmolality. The other conditions listed don’t cause this salty-sweat pattern, so they don’t fit this clue.